From lab idea to vaccine in your arm
Process map by Brian. 36 steps, 2 layers. Tags: science, health, biology.
- Researchers: Identify a target on the germ (an antigen)
- Researchers: Design candidate vaccines
- Researchers: Test in cells and animals
- Researchers: Safe, and triggers an immune response?
- Volunteers: Phase 1: a few dozen volunteers. Is it safe?
- Researchers: Safe at this dose?
- Volunteers: Phase 2: hundreds of volunteers. Right dose?
- Researchers: Strong immune response?
- Volunteers: Phase 3: tens of thousands, half get a placebo
- Regulators: Regulators review every piece of data
- Regulators: Benefits clearly outweigh risks?
- The factory: Manufacture at scale with strict quality checks
- Clinics and you: Distribute it cold to clinics
- Clinics and you: You roll up your sleeve
- Clinics and you: Safety monitoring continues for years
- Researchers: Provide more data
- Researchers: Adjust the dose or ingredients
- Researchers: Stop the program and publish what was learned